OC-025 PROSPECTIVE STUDY OF THE ANALGESIC EFFICACY OF A CYCLOMESH™ PARIETAL REINFORCEMENT IMPLANT SOAKED IN ROPIVACAINE IN THE TREATMENT FOR UNCOMPLICATED INGUINAL HERNIA

Abstract Background The objective of this study was to evaluate the interest a parietal prosthesis (Cyclomesh ™) soaked with ropivacaine in management early postoperative pain. Materials and Methods This is randomized, phase III, comparative superiority, double-blind, international multicentre study. 290 patients (October 2019 February 2022) underwent surgery for inguinal hernia, by Liechtenstein technique, under general anaesthesia, placement or saline prosthesis. primary endpoint coughing pain assessment (EVA) at H6. secondary endpoints were overall H2, H4 H6 evaluation painkillers consumption. Results type had no significant effect on H6, either ITT population (3.3 vs 3.2, p=0.12) PP 3.7, p=0.15). ropivaciane resulted decrease H2 (2.3 p<0.0001), 3.1, p<0.0001) 2.7, p=0.0039). Regarding consumption, complications number ambulatory conversions, there difference between two groups. Conclusion did not reduce but allowed over first 6 hours after could simplify patients.